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The basics of genetics Item Preview. EMBED for wordpress. The stereotypical double helix, DNA features two parallel twisting sides made of sugar and phosphate molecules, connected by rungs featuring pairs of individual nucleotides: Adenine AThymine TGuanine Gand Cytosine C.
A always goes with T, and C always goes with G. The order of these individual strands is basically a code for your genetic programming. These genes are specific sequences that code individual proteins. So, for Free (Original) - Genetic Line - Be Free (CD), one section of your DNA may be the gene for coding your hair texture, while another determines your eye color.
DNA molecules, containing the genes, are wrapped around proteins to form individual packets called chromosomes - 23 pairs to be exact! These 23 chromosomes are in the nucleus of each cell.
Basically, the entire genetic code for your entire self is stored everywhere throughout your self. Pretty cool! It's the differences in the. The overall picture of this genetic identity is referred to as a Free (Original) - Genetic Line - Be Free (CD). Whenever your cells replicate, they copy the DNA for new cells.
These errors are known as SNPsor single nucleotide polymorphisms. SNPs have the potential to up or down regulate gene function, and potentially change the type of protein coded for by the gene. Since we have two copies of most of our genes - one from mom and one from dad - either copy can potentially contain a SNP mutation.
Thankfully, most SNPs aren't a big deal. In fact, an estimated 1 out of nucleotides features a SNP, meaning the average human may have around 10 million SNPs! Some SNPs, however, can affect the function of genes. It can make them defective, and function at less than optimal levels.
On the contrary, it could make them unregulated, and over perform. In any case, it does not tend to make the gene completely defunct. Some SNPs can influence a person's propensity towards certain disease states, reactions to food and environmental toxins, or drug interactions.
We are actually born with most of our SNPs, which are passed on hereditarily, explaining why certain diseases can be "hereditary. Unless you happen to have DNA analyzing equipment chilling in your basement if so, Free (Original) - Genetic Line - Be Free (CD), can we be friends?
I haven't personally used 23andMe, as I found the free alternative discussed in a bit. After a brief hiatus, 23andMe gained FDA approval for modified health reports which simply indicate whether you are a carrier for a select number of "approved" disease risk genes.
In any case, I'll be showing you how to hardcore analyze your raw genetic data through other online services. It's called Genes for Good. It's not just free, it's super free, in a they-even-pay-for-postage type way. Genes For Good is a research project run by the University of Michigan, which aims to discover disease cures by analyzing the genetic data, lifestyle, and health of thousands of participants.
As of Octoberthe study has over 15, participants, with over 4, genotypes analyzed. Note: I do wonder how long the project will continue, since the study states they would continue through 5, spit tests.
To enroll in Genes For Good, visit their Facebook app. Once you create an account as a "Regular" member, you can begin the steps to receive the genetic spit kit.
You have to complete 15 Health History surveys and 20 Health Tracking surveys. You can knock out all the health history surveys at once in an hour or so if you like.
Unless you make the mistake I did of taking the "Patterns" study, with 30 pictures featuring a missing piece. Though it claimed it would only take 20 minutes, I resolved to solve every single oneand found myself intensely staring at the computer Free (Original) - Genetic Line - Be Free (CD) for hours.
For example, "Alcohol Use" asks how much and what you drank the prior night, and "Weight" simply asks your weight, and if you got on a scale to check. The only catch is you have to do these over the course of a few days two or more times, in a span of 8 or more days.
Once you complete the minimum amount of surveys, you transition from a "Regular" member to a "Silver" member. You're now eligible for a spit kit! At this point, you fill Free (Original) - Genetic Line - Be Free (CD) a variety of wavers indicating your volunteer status and acknowledging the implications of the program, such as the presence of genetic information in your saliva which hopefully you're aware of by this point.
Some key takeaways to what you're signing : your DNA will be "frozen and stored indefinitely in a secure laboratory," your DNA data may be released in an un-identified form to qualified researchers who will not attempt to pursue identification, any personal information will be approved by institutional review boards, and the Genes For Good researchers hold a "Certificate of Confidentiality" from the National Institutes of Health to protect participants.
The only information available to Facebook is your App use, but not the information collected. Within 2 weeks, you should receive your spit test in the mail. The kit includes a physical copy of the study information and consent form, the spit kit collection system, and an addressed return bubble envelope, complete with postage. Being the obsessive control freak worrier I am, I added my own extra postage just in case.
Collecting your spit is a super fun experience reminiscent of Dexter's Laboratory.
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